Phagocytosis of <i>Mycobacterium tuberculosis</i>: A Narrative of the Uptaking and Survival

Mycobacterium tuberculosis is the causal agent of human tuberculosis. The initial events establishment infection include phagocytosis by several innate immune response cells. This chapter will discuss cells involved, phagocytic pattern recognition receptors (PPRs) that recognize and mediate bacteria (such as C-type lectin receptors, Toll-like complement scavenger receptors), outcome this interaction. Additionally, bacterial strategies to evade response—which includes inhibition phagosome maturation arresting acidification, mechanisms survive reactive nitrogen species oxygen species, finally, resistance apoptosis autophagy—will be reviewed. Finally, host-pathogen interaction M. with during primary also